Opsynvi (Macitentan/Tadalafil)

Opsynvi Information:

Buy Opsynvi

Opsynvi (Macitentan/Tadalafil) is used to treat pulmonary arterial hypertension, a condition characterized by high blood pressure in the arteries of the lungs. Its active ingredients are macitentan, an endothelin receptor antagonist, and tadalafil, a phosphodiesterase 5 (PDE5) inhibitor. This combination medication works by relaxing and widening the blood vessels in the lungs, thus lowering the blood pressure. Macitentan achieves this by blocking endothelin, a substance that narrows blood vessels. At the same time, tadalafil inhibits PDE5, an enzyme that breaks down a substance that relaxes smooth muscle. As a result, Opsynvi helps to prevent the worsening of the condition and frequent hospitalization while improving exercise ability.

Generic Opsynvi from Canada

Canada Drugs Online proudly serves you the brand Opsynvi, manufactured by Janssen from Canada. The generic Opsynvi is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Pulmonary arterial hypertension (PAH) such as Adcirca and Revatio.

Opsynvi Side Effects:

Common mild side effects of this medication include runny nose, sore throat, cough, chills, dizziness, headache, muscle pain, flushing, nausea, vomiting, or stomach upset. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include pale skin, abnormal heartbeat, persistent nausea and vomiting, severe abdominal pain, yellow eyes and skin, sudden vision problems, hearing abnormalities, painful or prolonged erection, severe body itching and rash, swelling of your face, lips, tongue, or throat, difficulty in breathing, and extreme dizziness while taking this medication. Also, inform your doctor about other side effects you noticed not listed here.

Opsynvi Directions:

Take Opsynvi tablets orally once daily, with or without food. Swallow the tablet whole; do not crush or chew it. Depending on your condition, your doctor will determine the appropriate dose for you. Take it at the same time each day for optimal effectiveness. If you miss a dose, take it as soon as you remember; avoid taking a double dose at once. Check out the leaflet in the medication pack for more usage details. Store this medication at room temperature and keep it out of the reach of children.

Opsynvi Precautions:

Before taking this medication, ensure you inform your doctor about any past or current personal or family history of medical conditions, especially the following:
• Allergic reaction to macitentan, tadalafil, other ingredients of Opsynvi, or any other medicine;
• Bleeding of blood disorders;
• Cancers;
• Dehydration;
• Eye problems;
• Heart disease;
• High or low blood pressure;
• Kidney disease;
• Liver problems;
• Penile conditions such as priapism and Peyronie’s disease;
• Stroke

Avoid consuming alcohol and smoking cigarettes while taking this medication, as these substances can increase the risk of side effects. This medication can cause dizziness and lightheadedness, so avoid driving or operating heavy machinery until you know how the medication affects you. Due to congenital disability risks, pregnant women must not take this medication. You will need to do a pregnancy test before taking this medication. You may also need to use a reliable form of birth control method while taking this medication. Consult your doctor immediately if you become pregnant while taking this medication. It should not be used by breastfeeding women due to the possible risk to infants. Some medicines can interact with the active ingredients in Opsynvi, leading to unwanted side effects or reduced effectiveness. Some of these drugs include:
• Antifungal medicines such as ketoconazole and itraconazole;
• Anti-seizure medicines such as carbamazepine;
• Erectile dysfunction medicines such as sildenafil;
• Riociguat

Therefore, you must inform your healthcare provider about all the medications, including herbal medicines and supplements, you are taking before starting Opsynvi to prevent drug interactions.