Akynzeo (Netupitant/Palonosetron)

Akynzeo Information:

Buy Akynzeo

Akynzeo (Netupitant/Palonosetron) is used, along with other medications such as metoclopramide, to prevent nausea and vomiting caused by chemotherapy, particularly in patients being given highly emetogenic chemotherapy drugs. Its active ingredients include Netupitant and Palonosetron. Akynzeo belongs to the class of drugs known as antiemetics. Netupitant is a neurokinin-1 (NK-1) receptor antagonist that blocks the action of substance P, a neurotransmitter involved in nausea and vomiting. Palonosetron is a serotonin 5-HT3 receptor antagonist that works by blocking serotonin, another neurotransmitter linked to nausea and vomiting. Together, these active ingredients target multiple pathways in the body associated with nausea and vomiting, providing a more comprehensive antiemetic effect for patients undergoing chemotherapy.

Generic Akynzeo from Canada

Canada Drugs Online is proud to serve you the brand Akynzeo Canada, manufactured by Purdue and Australia by a different manufacturer. The generic form of this medication is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Cancer Medications such as Afinitor and CeeNU.

Akynzeo Side Effects:

Common mild side effects of this medication include headache, weakness, indigestion, fatigue, constipation, and skin redness. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include a fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea, vomiting, and diarrhea, twitching muscles, unexplained fever, unusual agitation or restlessness, severe body itching, rash, swelling of your face, lips, tongue, or throat, difficulty breathing, and dizziness. Discontinue this medication and seek immediate medical attention if you observe these severe side effects. Additionally, inform your doctor about any other side effects not listed here.

Akynzeo has been established to be safe and effective in preventing nausea and vomiting caused by chemotherapy, with adverse effects typically mild. It is more effective in preventing emesis than when either of the active ingredients is used alone. It also maintains its antiemetic effect after repeated chemotherapy cycles. The half-life of Akynzeo can vary based on the specific component. The half-life of netupitant is approximately 90 hours, while the half-life of palonosetron is around 40 hours.

Akynzeo Directions:

This medication is available as a capsule and is usually taken with or without food, with each dose usually taken about 1 hour before the start of chemotherapy. Your doctor will determine the appropriate dose for you. Take this medication as directed by your doctor. Also, check out the leaflet in the medication pack for more usage details. Store at room temperature and keep away from pets and children.

Akynzeo Precautions:

Before using this medication, it is highly important to inform your doctor of any medical condition you have or had, especially:
• Allergic reactions to netupitant, palonosetron, other ingredients of Akynzeo, or any other medication or substances;
• Kidney disease;
• Liver disease

Consult your doctor before using this medication during pregnancy or while breastfeeding. Use this medication with caution in elderly individuals as they have a greater propensity for developing adverse effects. It is not suitable for use in individuals younger than 18 years. Certain medications can interact with netupitant and palonosetron, affecting their action in the body. Some of these drugs include:
• Antidepressants such as fluoxetine and paroxetine;
• Apomorphine;
• Elacestrant;
• Flibanserin;
• Lomitapide

Therefore, before taking Akynzeo, it is important to inform your doctor about any medication you are currently taking, including herbal medications and supplements, to determine if they can interact with netupitant and palonosetron.