Duavee (Conjugated Estrogens/Bazedoxifene Acetate)

Duavee Information:

Buy Duavee

Duavee (Conjugated estrogen/Bazedoxifene Acetate) is used to treat moderate to severe vasomotor symptoms (such as hot flushes) associated with menopause and to prevent postmenopausal osteoporosis in women with an intact uterus. Its active ingredients are conjugated estrogens and bazedoxifene acetate. Conjugated estrogens are a form of estrogen hormone replacement therapy that alleviates menopausal symptoms and prevents bone loss. Bazedoxifene acetate is a selective estrogen receptor modulator (SERM) that helps reduce the risk of endometrial hyperplasia, a condition that is a precursor to endometrial cancer that can occur with estrogen-alone therapy. Duavee works by combining the benefits of estrogen replacement with the protective effects of a SERM, addressing menopausal symptoms and preventing bone loss while mitigating the risk of estrogen-induced endometrial hyperplasia.

Generic Duavee from Canada

Canada Drugs Online proudly serves you the brand Duavee (Duavive) manufactured by Pfizer from Canada. The generic version is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Menopausal Hormone Therapies such as Estradot and Activella.

Duavee Side Effects:

Mild side effects of this medicine include nausea, vomiting, bloating, breast tenderness, headache, upset stomach, and weight changes. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include nausea or vomiting that doesn't stop, lumps in the breast, abnormal mental and mood changes, severe abdominal pain, yellowing eyes and skin, dark urine, swelling of the hands, ankles, and feet, increased thirst and urination, unusual vaginal bleeding (such as spotting, sudden heavy bleeding), high blood pressure, chest, jaw, or left arm pain, confusion, coughing up blood, pain, swelling or warmth in the groin and calf, trouble speaking, sudden dizziness, fainting, sudden and severe headache, sudden vision changes (such as partial/complete blindness), tingling, weakness or numbness in the arms and legs, trouble breathing, unusual sweating, weakness on one side of the body, severe body itching and rash, swelling of your face, lips, tongue, or throat, and extreme dizziness. Stop using this device and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about other side effects you see that are not listed here.

Clinical studies have demonstrated that Duavee is effective in reducing menopausal hot flashes and preventing postmenopausal osteoporosis. It has been shown to significantly decrease the frequency and severity of hot flushes, improve sexual functioning, and increase bone mineral density and overall quality of life. Safety studies indicate that while Duavee is generally well-tolerated, it carries risks similar to other hormone therapies, including an increased risk of blood clots and potential cancer risks. It is also worth noting that the addition of bazedoxifene acetate significantly reduces the risk of endometrial hyperplasia, a precursor to developing endometrial cancer. However, regular monitoring and individual risk assessment are recommended (source).

Duavee Directions:

Take Duavee tablets as your doctor prescribes or as stated in the medication pack. Take this medicine with or without food and swallow each tablet whole. You may take it with food or right after a meal to prevent stomach upset. Your doctor will determine the appropriate dosage schedule and duration of use for you. Do not use more than the prescribed dose. Store this medicine at room temperature and keep it away from children and pets.

Duavee Precautions:

Before using this medication, ensure that you inform your doctor about any prior or current medical conditions, including the following:
• Allergic reaction to conjugated estrogens, bazedoxifene acetate, other ingredients of Duavee, or any other medication;
• Asthma;
• Blood clotting or bleeding disorders;
• Bone diseases such as osteoporosis;
• Cancers such as breast cancer, ovarian cancer;
• Dementia;
• Diabetes, high blood pressure, or heart disease;
• Endometriosis;
• Eye disorders;
• Fibroid;
• Gallstones;
• High blood cholesterol levels;
• Kidney or liver disease;
• Migraines;
• Seizure disorders;
• Stroke;
• Thyroid problems;
• Unexplained vaginal bleeding

Avoid smoke or the intake of alcohol and alcoholic beverages while taking this medication to minimize the risk of adverse effects, especially in women older than 35 years. Inform your physician if you are having surgery because this medication might need to be stopped to prevent the development of blood clots during prolonged bed rest after surgery. Pregnant or breastfeeding women should not use this medication. It is also not for use in children. This medication can make your skin more sensitive to sunlight, leading to burns. Therefore, limit the exposure of your skin to the sun or fire while using this topical medication. Also, ensure you wear protective clothing when outdoors. Duavee can interact with other medications, increasing the risk of developing side effects. Some of these other medications include:
• Aromatase inhibitors such as anastrozole, and exemestane;
• Fondaparinux;
• Heparin;
• Ketoconazole;
• Other estrogen-containing medications;
• Tamoxifen;
• Quinidine

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe along with Duavee.