Estradot (Estradiol-17B)

Estradot Information:

Buy Estradot

Estradot (Estradiol-17B) is used to manage menopausal and postmenopausal symptoms in women, such as hot flashes, night sweats, and vaginal dryness, associated with a natural or surgically induced deficiency in estrogen. It may also be used along with other therapies to prevent osteoporosis associated with a lack of estrogen in menopausal and postmenopausal women. It belongs to the class of drugs known as hormone replacement therapy (HRT). Estradot delivers estradiol-17β through the skin into the bloodstream, maintaining stable hormone levels. Estradiol-17β mimics the natural estrogen produced by the ovaries, binding to estrogen receptors in various tissues, which helps regulate functions impacted by decreased estrogen levels during menopause.

Generic Estradot from Canada

Canada Drugs Online proudly serves you the brand Estradot manufactured by Novartis from Canada. The generic Estradot comes from a different manufacturer in Canada. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Menopausal Hormone Therapies such as Estalis Patches and Premain Vaginal cream.

Estradot Side Effects:

Notable mild side effects of this medication include acne, bloating, breakthrough menstrual bleeding or spotting, breast pain, change in sex drive, contact lens discomfort, redness, irritation, or darkening of the skin around areas where the patch is applied, dizziness, headache, migraine headache, mood swings, nausea, and weight changes. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include abdominal pain with nausea or vomiting, breast lumps, easy bruising and bleeding, frequent or prolonged heavy periods, fast or pounding heartbeat, swelling of the lower legs, ankles, feet, or fingers, high blood pressure, irritability, migraine headaches, pain in groin or calf, yellowing of the skin or whites of the eyes, dark urine, pale stools, difficulty breathing, chest pain, pain extending through shoulder and arm, coughing, coughing up blood, sweating, depression, sudden weakness or numbness in arms or legs, difficulty speaking, severe body itching and rash, swelling of your face, lips, tongue, or throat, and extreme dizziness. Stop using this device and seek immediate medical attention if you notice these severe side effects. Also, inform your doctor about other side effects you see that are not listed here.

Estradot is safe and effective in relieving menopausal symptoms like hot flashes and vaginal atrophy. Clinical studies show that Estradot can reach adequate blood levels with lower doses than oral estradiol. This can reduce the risk of side effects that usually happen with higher estrogen levels in the body. However, the safety profile of hormone replacement therapies (HRT), including Estradot, suggests some increased risks of serious adverse effects such as venous thromboembolism (VTE), stroke, and, with prolonged use, breast cancer and possibly ovarian cancer. These risks are higher in older women and those with other predisposing factors. Despite these risks, the benefits of symptom relief and quality of life improvement with this medication can be substantial, mainly when used at the lowest effective dose for the shortest duration necessary.

Estradot Directions:

Estradot comes in the form of a transdermal patch, which should be applied to the skin of the buttocks, lower back, lower abdomen, or hip. The applied patch should be changed twice weekly (i.e., every 3-4 days). Rotate the application site each time to avoid skin irritation. Talk to your doctor about the dosage schedule and the appropriate application site. Other medicines may be prescribed along with this patch if you have undergone a surgical removal of your uterus. Ensure you check out the leaflet in the medication pack for more instructions on usage. Store this medication at room temperature and keep it out of the reach of children. Do not store the patches out of the pouch.

Estradot Precautions:

Before applying this medication, ensure that you inform your doctor about any prior or current medical conditions, including the following:
• Allergic reaction to estradiol, other ingredients of this transdermal patch, or any other medication;
• Active phlebitis (inflamed varicose veins);
• Asthma;
• Blood clotting or bleeding disorders;
• Bone diseases such as osteoporosis;
• Cancers such as breast cancer, endometrial cancer, and ovarian cancer;
• Dementia;
• Diabetes, heart disease, high blood pressure;
• Endometriosis;
• Eye disorders;
• Fibroid;
• Gallstones;
• High blood cholesterol levels;
• Kidney or liver disease;
• Migraines;
• Seizure disorders;
• Stroke;
• Thyroid problems;
• Unexplained vaginal bleeding

It is important to have follow-up visits with your doctor 3 to 6 months after starting this medication to assess your treatment response and screen for potential adverse effects. Pregnant or breastfeeding women should not use this medication. This medication can make your skin more sensitive to sunlight, leading to burns. Therefore, limit the exposure of the applied skin to the sun or fire while using this topical medication. Also, ensure you wear protective clothing when outdoors. Estradiol can interact with various other medications, thereby increasing the risk of developing side effects. Some of these other medications include:
• Anti-anxiety medicines such as barbiturates and meprobamate;
• Antibiotics and other anti-infective medicines such as rifampicin erythromycin;
• Anti-inflammatory medicine called phenylbutazone

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including other topical medicines, to determine if it is safe along with Estradot.