Ibrance (Palbociclib)

Ibrance Information:

Buy Ibrance

Ibrance (Palbociclib) is used to treat various forms of breast cancer, including hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. It is typically prescribed in combination with hormone therapy, such as letrozole or fulvestrant, to enhance its effectiveness against breast cancer that has either advanced or spread to other parts of the body. It contains the active ingredient palbociclib, which belongs to the class of drugs known as cyclin-dependent kinase (CDK) 4/6 inhibitors. Ibrance works by inhibiting CDK4 and CDK6, enzymes that are crucial for cell division. Ibrance disrupts the cancer cell cycle by blocking these enzymes, preventing cancer cells from growing and dividing.

Generic Ibrance from Canada

Canada Drugs Online proudly serves you the brand Ibrance, manufactured by Pfizer from Canada and New Zealand. The generic form of this medication is currently not available. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Cancer medications such as Bosulif and Jakavi.

Ibrance Side Effects:

Common mild side effects of this medication include nausea and vomiting, mouth sores, hair loss, diarrhea, decreased appetite, and body weakness. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include fever, shortness of breath, pale or yellowish skin, easy bruising or bleeding, frequent infection, unusual weakness or tiredness, dizziness, lightheadedness, or feeling like you are about to pass out, headache, fast or abnormal heartbeat, cough, persistent nausea or vomiting, severe dizziness, feeling lightheaded, or fainting, severe body itching, rash, swelling of your face, lips, tongue, or throat, difficulty breathing, and dizziness. If you observe these severe side effects, discontinue this medication and seek immediate medical attention. Additionally, inform your doctor about any other side effects not listed here.

Clinical studies have demonstrated that Ibrance, when combined with hormone therapy, significantly improves progression-free survival in patients with HR+, HER2- advanced or metastatic breast cancer compared to hormone therapy alone. The safety profile highlights common issues like neutropenia, but overall, the drug is considered well-tolerated with manageable side effects (source).

Ibrance Directions:

Take this medication at the same time each day with or without food, as your doctor prescribes. Your doctor will determine the appropriate dosage schedule and duration depending on your condition and response to treatment. Swallow the tablet whole with a glass of water. Do not chew or crush the tablets. Do not split the tablets before swallowing. Avoid the intake of grapefruits while using this medicine. Check out the leaflet in the medication pack for more details on usage. Store at room temperature and keep away from pets and children.

Ibrance Precautions:

Before using this medication, it is essential to inform your doctor of any medical condition you have or had, especially:
• Allergic reaction to palbociclib, other ingredients of this medication, or any other medicine;
• Active infections;
• Kidney disease;
• Liver disease

This medication should not be used during pregnancy or while breastfeeding. Women using this medicine should be on reliable contraceptives until at least three weeks after the last dose. Use this medication with caution in elderly individuals as they have a greater propensity for developing adverse effects. Certain medications can interact with palbociclib, affecting their action in the body. Some of these drugs include:
• Apalutamide;
• Atazanavir;
• Carbamazepine;
• Isoniazid;
• Phenytoin;
• Voxelotor

Therefore, before taking Ibrance, you must inform your doctor about any current medication, including herbal medicines and supplements, to determine if they can interact with palbociclib.