Janumet XR (Sitagliptin/Metformin XR)

Janumet XR Information:

Buy Janumet XR

Janumet XR is an extended-release oral medication used to manage type 2 diabetes mellitus in adults. It combines two active ingredients, sitagliptin and metformin hydrochloride. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin production and reduce glucose production in the liver. Metformin, a biguanide, decreases the liver's glucose production and improves the body's response to insulin. Together, these two ingredients help control blood sugar levels more effectively than either medication alone.

Your doctor may prescribe Janumet XR when diet and exercise alone cannot control blood sugar levels or when metformin alone is inadequate. The extended-release formulation allows for once-daily dosing, which may improve treatment adherence and minimize gastrointestinal side effects associated with immediate-release metformin. It is usually taken with the evening meal to reduce stomach upset.

Janumet XR from Canada

Canada Drugs Online offers Janumet XR, manufactured by Merck in Canada. A different manufacturer also makes the generic Sitagliptin/Metformin XR available in Canada. For further information or to purchase, please call our toll-free number at 1-877-900-3784.

CanadaDrugsOnline.com provides a range of Diabetes medications, such as Janumet and Jardiance.

Janumet XR Side Effects:

Like all medications, Janumet XR may cause side effects, although not everyone will experience them. Common side effects include:
• Abdominal discomfort;
• Cold symptoms such as runny or stuffy nose, sneezing, sore throat;
• Diarrhea;
• Gas (flatulence);
• Headache;
• Loss of appetite;
• Low blood sugar;
• Nausea;
• Vomiting

These mild side effects may improve as the body adjusts to the medication. However, in rare instances, more serious side effects may occur, such as:
• Allergic reactions, including swelling of the face, lips, tongue, or throat;
• Heart failure symptoms, such as shortness of breath, swelling in the legs, or rapid weight gain;
• Hypoglycemia (low blood sugar), primarily when used with other diabetes medications;
• Lactic acidosis symptoms, including unusual muscle pain, coldness, trouble breathing, dizziness, weakness, stomach pain, vomiting, irregular heart rate;
• Liver enzyme abnormalities or hepatitis;
• Little or no urination;
• Pancreatitis, which may cause severe stomach pain and vomiting;
• Severe or ongoing joint pain;
• Skin reactions, including blistering or rash

Seek medical attention immediately if you experience symptoms of lactic acidosis, pancreatitis, or a severe allergic reaction.

Janumet XR Directions:

For best results, follow the instructions provided by your healthcare provider or those specified on the product label. General directions for use include:
1. Take Janumet XR exactly as your doctor prescribed.
2. Swallow the tablet whole with a full glass of water.
3. Take it once daily with an evening meal to reduce stomach upset.
4. Do not crush, chew, or split the tablet.
5. Follow a healthy diet and exercise routine as part of your diabetes management plan.
6. Monitor your blood sugar levels regularly as directed by your doctor.
7. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not take two doses at the same time.

Store at room temperature (15-30°C) in a dry place. Keep the medication out of the reach of children and avoid exposure to excessive heat or moisture.

Janumet XR Precautions:

Do not use Janumet XR if you are allergic to sitagliptin, metformin, or other ingredients in the formulation. Inform your doctor if you have any of the following conditions:
• Alcohol use disorder, as it increases the risk of lactic acidosis;
• Congestive heart failure or other heart conditions;
• Gallstones;
• High triglyceride levels (a type of fat in the blood);
• Kidney disease or reduced kidney function;
• Liver disease, including hepatitis or cirrhosis;
• Metabolic acidosis or diabetic ketoacidosis;
• Pancreatitis or a history of pancreatic disease;
• Severe infection or dehydration

Janumet XR may interact with other medications, including diuretics, corticosteroids, and beta-blockers. Always inform your healthcare provider of any other treatments you are using, including over-the-counter products, vitamins, or herbal supplements. You may need to temporarily stop taking this medication if you have an x-ray or CT scan using a dye injected into your veins.

If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Janumet XR. This medication may affect your blood sugar levels, and adjustments to your diabetes treatment plan may be necessary. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis. Regular kidney and liver function tests may be required to ensure the safe use of Janumet XR. Research has not yet proven the efficacy of this medication in children under the age of 18.