Afinitor (Everolimus)

Afinitor Information:

Buy Afinitor

Afinitor (Everolimus) is used to treat various types of cancer, including advanced breast cancer, pancreatic neuroendocrine tumors, and advanced renal cell carcinoma. It is also prescribed to treat non-malignant conditions such as subependymal giant cell astrocytoma (SEGA) and noncancerous kidney tumors associated with tuberous sclerosis complex. Furthermore, it is used with other medications to treat partial onset seizures associated with tuberous sclerosis complex. The active ingredient in Afinitor is everolimus, which belongs to a class of drugs known as mTOR inhibitors. Everolimus works by blocking the mTOR protein kinase, which plays a crucial role in the signaling pathways involved in cell growth, proliferation and survival. By blocking the activity of mTOR, Afinitor interferes with the abnormal growth and division of cancer cells. This process helps to slow down or stop the progression of cancer. Additionally, Afinitor may also inhibit angiogenesis, the process by which tumors form new blood vessels to supply themselves with nutrients and oxygen, further impeding tumour growth.

Generic Afinitor from Canada

Canada Drugs Online proudly serves you the brand Afinitor from Canada and New Zealand, manufactured by Novartis. The generic Afinitor is also available from Canada by a different manufacturer. Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Cancer Medications such as Gleevec and Zytiga.

Afinitor Side Effects:

Common mild side effects of this medication include diarrhea, nausea, vomiting, decreased appetite, weight loss, changes in taste, nosebleeds, dry skin, dizziness, headache, pain or sores in the mouth and throat, and temporary hair loss. To reduce the risk of mouth sores, brush your teeth regularly and avoid using mouthwash containing alcohol, iodine, peroxide, or thyme. Also, eat more soft and moist food while taking this medication. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include swollen hands, ankles, and feet, missed/heavy or painful periods, easy bruising or bleeding, unusual tiredness, mental or mood changes, delayed wound healing, an abnormal change in the amount of urine, high blood sugar, increased thirst and urination, increased cholesterol levels, sore throat that doesn't go away, fever, chills, cough, shortness of breath, chest pain, severe nausea and vomiting, loss of appetite, dark urine, abdominal pain, yellow eyes and skin, clumsiness, loss of coordination, weakness, confusion, difficulty concentrating, difficulty moving your muscles, problems with speech, seizure, vision changes, severe body itching, rash, swelling of your face, lips, tongue, or throat, and dizziness. If you notice severe side effects, stop taking this medication immediately and seek medical attention. Additionally, inform your doctor about any other side effects not listed here.

Clinical trials show everolimus is a safe and effective long-term treatment for various tumors, both malignant and non-malignant. It produces sustained therapeutic effects in cancer management with high tolerability and low risk of severe adverse effects. The half-life of everolimus is approximately 30 hours.

Afinitor Directions:

Afinitor is available as a tablet and is prepared for oral use as directed by your doctor. It is also available as tablets for oral suspension. Take this medication at the same time each day, with or without food. Your doctor will determine the appropriate dose, formulation and duration of treatment for you. Check out the leaflet in the medication pack for detailed usage instructions. Store either form of this medication at room temperature (20-25⁰C) and keep away from children and pets.

Afinitor Precautions:

Before starting this medication, ensure that you inform your doctor about any prior or current medical conditions, including the following:
• Allergic reaction to everolimus, other ingredients of Afinitor, or any other medications;
• Current infections;
• Diabetes;
• High cholesterol levels;
• Liver disease;
• Radiation treatment

Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how this medication affects you, as this medication can sometimes cause dizziness. Do not smoke or take alcohol and alcoholic beverages while using this medication to avoid developing side effects. Avoid grapefruit and grapefruit juice while you are on Afinitor. This medication can make you more susceptible to infections. Minimize the risk of infection by avoiding contact with those sick with measles, chickenpox, or the flu. Inform your healthcare provider that you use this medication before getting a vaccine or undergoing surgery. It is advised to apply caution with sharp objects and to avoid participating in any activity or sport that may result in serious injury while taking this medication. This medication is not suitable for use during pregnancy. Pregnant women should not handle this medication as it can be absorbed into the body through the skin and the lungs, potentially causing harm to the unborn baby. Women are advised not to breastfeed while taking this medication until two weeks after the last dose. Both men and women taking this medication should employ the use of reliable birth control methods during treatment till eight weeks after taking the last dose of this medication. Afinitor should not be used in individuals younger than 18 years.

Everolimus can interact with various other medications, thereby increasing the risk of developing side effects. Some of these other medications include:
• ACE inhibitors such as captopril and lisinopril;
• Antibiotics such as clarithromycin and erythromycin;
• Antifungals such as itraconazole and ketoconazole;
• HIV medications such as atazanavir and indinavir;
• Immune modulators such as natalizumab and rituximab

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe for use along with Afinitor.