Emend (Aprepitant)

Emend Information:

Buy Emend

Emend (Aprepitant) is used to prevent nausea and vomiting associated with highly emetogenic chemotherapy drugs, such as cisplatin. It is an antiemetic medication whose active ingredient is aprepitant, belonging to the class of neurokinin-1 (NK1) receptor antagonists. Aprepitant works by blocking NK1 receptors in the brain, which prevents the binding of substance P, a neuropeptide involved in the vomiting reflex. By inhibiting this pathway, Emend effectively reduces both acute and delayed phases of nausea and vomiting, mainly when combined with other antiemetic agents like corticosteroids and 5-HT3 antagonists.

Generic Emend from Canada

Canada Drugs Online proudly offers the brand Emend and Emend Tri-Fold Pack, manufactured by Merck in Canada. The generic Emend Tri-Fold comes from India also called Aprecap by Glenmark. For details, please call us toll-free at 1-877-900-3784.

CanadaDrugsOnline.com also carries other Cancer medications such as Arimidex and Eloxatin.

Emend Side Effects:

Common mild side effects of this medication include abdominal pain, changed sense of taste, constipation, diarrhea, dizziness, dry mouth, fatigue, flushing, hair loss, headache, hiccups, loss of appetite, muscle cramps, upset stomach, vomiting, and weakness. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include anxiousness, fever, low blood pressure, increased sweating, painful, burning urination, red, itchy eyes with discharge, ringing in the ears, prolonged dizziness, headache, stiff neck, weight loss, or listlessness, severe body itching, rash, swelling of your face, lips, tongue, or throat, difficulty breathing, and dizziness. If you observe these severe side effects, discontinue this medication and seek immediate medical attention. Additionally, inform your doctor about any other side effects not listed here.

Clinical studies have shown that Emend (aprepitant) is effective in preventing nausea and vomiting associated with highly emetogenic chemotherapy drugs. It significantly improves control over these symptoms when combined with other antiemetic agents. It is generally well-tolerated, though some side effects include fatigue and gastrointestinal issues (source).

Emend Directions:

Emend is available in capsules with different dosage strengths. At the same time, the Emend Tri-Fold Pack contains two 80 mg capsules and one 125 mg capsule. The recommended dose of aprepitant is 125 mg taken by mouth 1 hour before chemotherapy and 80 mg once daily in the morning for the next two days following chemotherapy. However, consult your doctor for the appropriate dose and duration of treatment for you. Aprepitant can be taken with or without food. Check out the leaflet in the medication pack for more instructions on usage. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Emend Precautions:

Before taking this medication, ensure you inform your doctor about any past or current personal or family history of medical conditions, especially the following:
• Allergic reaction to aprepitant, other ingredients of this medication, or any other medicine;
• Liver disease

This medication may reduce the effectiveness of hormonal birth control pills during aprepitant treatment and for 28 days after treatment. Use another (or backup) method of birth control during treatment and for one month following the last dose of this medication. Consult your doctor before using this medication during pregnancy or while breastfeeding. It is not recommended for use in children younger than 12 years. Some medicines may interact with aprepitant, leading to an increase in the risk of developing side effects. Some of these medications include:
• Amiodarone;
• Astemizole;
• Cisapride;
• Pimozide;
• Terfenadine

Therefore, before using this medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe along with Emend.