Nizoral (Ketoconazole)

Nizoral Information:

Buy Nizoral

Nizoral (Ketoconazole) is used to treat serious fungal infections that affect the whole body such as blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. It's typically given to patients who haven't responded well to other treatments or can't tolerate them. It is also used to prevent relapse of these fungal infections after initial treatment. The active ingredient in Nizoral is Ketoconazole, which belongs to the azole antifungal class of drugs. Ketoconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. By disrupting ergosterol synthesis, Ketoconazole weakens the fungal cell membrane, leading to cell death and inhibiting fungal growth and replication. This mechanism makes it effective against a wide range of fungal infections, both superficial and systemic. The oral formulation is only used for systemic fungal infections and is not recommended for fungal infections of the skin and nails.

Generic Nizoral from Canada

Canada Drugs Online is proud to serve you generic Nizoral (Ketoconazole) from Canada and India (Ketocip). Please call us toll-free at 1-877-900-3784 for details.

CanadaDrugsOnline.com also carries other Anti-Fungal Medications such as Clindesse and Lamisil 1%.

Nizoral Side Effects:

Common mild side effects of this medication include mild nausea, vomiting, mild abdominal discomfort, breast swelling, headache, and dizziness. Contact your doctor if these mild side effects persist or worsen.

Possible serious side effects of this medication include headache, vision changes, depression, thoughts of suicide, unusual tiredness, weakness, dizziness upon standing, diarrhea, weight loss, menstrual period changes, decreased sexual interest or ability, enlarged or tender breasts in men, upper stomach pain, fever, loss of appetite, dark urine, clay-colored stools, yellowness of the skin or eyes, severe nausea and vomiting, severe body rash, itching, swelling of the face, tongue, throat, and difficulty in breathing. Discontinue this medication and seek immediate medical attention if you observe these severe side effects. Additionally, inform your doctor about any other side effects not listed here.

Ketoconazole is one of the first broad-spectrum antifungal agents and has been established to be highly effective in treating fungal infections. However, there are growing concerns about its safety because it has a higher propensity of causing liver injury and adrenal gland problems. This is why it is only used when other first-line antifungal medicines have failed in treating the fungal infection. It is also contraindicated in individuals with liver and adrenal gland disease. Therefore, individuals taking this medication should be monitored closely by healthcare professionals for potential adverse effects. Oral Ketoconazole typically has a half-life of around 8 to 12 hours, meaning it takes this amount of time for half of the drug to be eliminated from the body.

Nizoral Directions:

This medication comes in tablets, which are usually taken with food to improve absorption and reduce the risk of stomach upset. Swallow the tablets whole with a full glass of water. It's typically taken once daily, but the dosage and frequency may vary based on the condition being treated. Consult your doctor for the appropriate dosage schedule for you. Do not take more than the prescribed dose or for longer than prescribed to avoid the risk of developing adverse effects. When using an antacid, it's important to take ketoconazole either two hours before or one hour after the antacid. Failing to do so could result in inadequate absorption of ketoconazole into the body. Store this medication at room temperature and keep it away from children and pets.

Nizoral Precautions:

Before using Nizoral, it is highly important to inform your doctor of any medical condition you previously or currently have, especially:
• Allergic reaction to Ketoconazole, other ingredients of Nizoral, or any other medication;
• Achlorhydria (low stomach acid production);
• Addison’s disease;
• Adrenal gland problems;
• Electrolyte imbalances such as low potassium levels;
• Heart disease;
• Liver disease;
• Low testosterone levels

While taking this medication, avoid smoking and the intake of alcohol or alcoholic drinks as they can cause adverse effects. Refrain from driving or operating machinery until you understand its impact on your alertness, as it can cause drowsiness or dizziness. This medication should be used with caution in elderly individuals as they are at higher risk of developing side effects. Do not use this medication during pregnancy or while breastfeeding unless recommended by your doctor after careful evaluation of its risk and benefits. Certain medications can interact with Ketoconazole, potentially increasing the risk of side effects. Some of these medications include:
• Antacids;
• Disopyramide;
• Dofetilide;
• Dronedarone;
• Isoniazid;
• Methadone;
• Nevirapine;
• Pimozide;
• Quinidine;
• Ranitidine;
• Rifampin

Therefore, it is crucial to discuss with your doctor all current medications you are taking, including herbal supplements, to determine potential interactions with Ketoconazole.